Description
Mary & May Spicule Retinol PDRN Cream is a high-performance treatment cream that combines innovative spicule technology with stabilized retinol to target multiple skin concerns at once. Formulated with 2,000 ppm of marine-derived micro spicules—tiny natural sponge particles smaller than pores—this cream helps improve ingredient absorption while gently supporting skin renewal for smoother, firmer-looking skin. Unlike traditional retinol creams, it’s designed to deliver visible results while helping minimize irritation.
What makes Mary & May Spicule Retinol PDRN Cream especially effective is its blend of nano liposome retinol, CICA PDRN, niacinamide, and barrier-supporting ingredients like panthenol, ceramide NP, and hyaluronic acid. Together, they help improve the appearance of fine lines, pore size, and skin texture while calming and strengthening the skin. It’s ideal for skin that feels dull, textured, or less resilient.
Key Benefits
- Smooths Fine Lines & Wrinkles — Nano liposome retinol helps improve visible signs of aging with enhanced stability and gentle delivery.
- Refines Enlarged Pores — Marine micro spicules help improve pore depth, density, and overall skin texture.
- Supports Skin Recovery — CICA PDRN helps soothe stressed skin while encouraging repair and resilience.
- Strengthens the Skin Barrier — Panthenol, ceramide NP, and hyaluronic acid help maintain hydration and comfort.
- Mary & May Spicule Retinol PDRN Cream for Targeted Renewal — A concentrated treatment for smoother, firmer, healthier-looking skin.
Hero Ingredients
Here’s what powers the Mary & May Spicule Retinol PDRN Cream:
Hydrolyzed Sponge (Marine Spicules)
These natural marine-derived micro spicules are 1/40 the size of pores and help create temporary micro-channels for better ingredient absorption. They also help refine rough texture and visibly improve skin smoothness. Mary & May uses 2,000 ppm, with approximately 180,000–200,000 spicules per jar.
Retinol (Nano Liposome Retinol)
A gold-standard ingredient for improving fine lines, wrinkles, and uneven texture. The nano liposome delivery system helps improve stability and absorption while reducing the irritation often associated with traditional retinol. Mary & May includes retinol at 1,000 ppm.
Sodium DNA (CICA PDRN)
A skin-repairing ingredient that helps support regeneration and recovery. It works to soothe stressed skin while improving resilience and supporting the skin’s natural renewal process.
Panthenol (Vitamin B5)
Included at 2%, panthenol helps calm irritation, strengthen the moisture barrier, and keep skin comfortable—even alongside active ingredients like retinol and spicules.
Niacinamide (Vitamin B3)
A multitasking ingredient that helps brighten dull skin, refine pores, and support smoother texture while reinforcing barrier health.
Ceramide NP
A skin-identical lipid that helps restore and protect the moisture barrier, reducing dryness and helping skin stay resilient.
Sodium Hyaluronate & Polyglutamic Acid
These moisture-binding ingredients help attract and retain hydration, keeping skin plump and balanced during the renewal process.
Best For
Ideal Skin Match:
✅ Normal Skin — texture renewal
✅ Combination Skin — balanced repair
✅ Oily Skin — pore refining
✅ Mature Skin — wrinkle care
✅ Dry Skin — barrier support
✅ Experienced Retinol Users — targeted anti-aging care
Targets These Skin Concerns:
Fine lines
Wrinkles
Enlarged pores
Rough texture
Loss of firmness
Dullness
Uneven skin texture
Barrier weakness
Why Choose Mary & May Spicule Retinol PDRN Cream?
- Combines spicule technology with stabilized retinol for enhanced results
- Helps improve wrinkles, pores, and texture at the same time
- Includes soothing and barrier-supporting ingredients to minimize discomfort
- Fragrance-free and essential oil-free formula
- Skin irritation test completed
- Ideal as a targeted nighttime treatment for visible skin renewal
Who Can’t Use This Product?
⚠️ Very sensitive or reactive skin — retinol and spicules may cause irritation or tingling
⚠️ First-time retinol users — start slowly and patch test before regular use
⚠️ Those using strong exfoliating acids or prescription retinoids — may increase sensitivity when layered together
⚠️ Avoid use on damaged or broken skin until fully healed
How to Use
Prep Your Skin — Start with clean, dry skin after toner or lightweight serum.
Apply a Small Amount — Use a pea-sized amount and spread evenly across the face, avoiding the eye and lip areas.
Press to Absorb — Gently press into the skin rather than rubbing to minimize irritation from the spicules.
Use at Night — Apply 2–3 times per week at first, then gradually increase as tolerated. Always wear sunscreen during the day.
Frequently Asked Questions
Q: What does Mary & May Spicule Retinol PDRN Cream feel like on the skin?
A: You may notice a mild tingling or prickling sensation due to the micro spicules. This is normal and typically fades as the product absorbs.
Q: Can I use Mary & May Spicule Retinol PDRN Cream every day?
A: If you’re new to retinol or spicule skincare, start 2–3 nights per week and increase gradually based on your skin’s tolerance.
Q: Is Mary & May Spicule Retinol PDRN Cream suitable for sensitive skin?
A: It includes soothing ingredients like panthenol and ceramide, but the retinol and spicules may still be too stimulating for highly sensitive skin. Patch testing is strongly recommended.
Q: Can I use this cream with other retinol products?
A: It’s best not to layer Mary & May Spicule Retinol PDRN Cream with other retinoids or strong exfoliating acids to avoid over-irritation.
Q: Does this cream help with pores and wrinkles?
A: Yes. The combination of retinol and spicules helps improve the appearance of enlarged pores, smooth fine lines, and refine overall skin texture with consistent use.
Disclaimer
Please check the product in front of the delivery person. Once delivery is completed, no complaints or exchanges will be accepted. Product packaging may change from time to time, so you may receive either the old or new version — this is completely normal.




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